|Keyword||CPC||PCC||Volume||Score||Length of keyword|
|htra1 and astrocyte||0.12||0.7||9300||81|
|htra1 recombinant protein||0.97||0.9||1033||95|
|htra1 membranous nephropathy||1.68||0.1||8521||95|
Learn more The HTRA1 gene provides instructions for making a protein that is found in many of the body's organs and tissues. This protein is a type of enzyme called a serine protease, which has an active center that cuts (cleaves) other proteins into smaller pieces.Is HtrA serine peptidase 1 (HTRA1) involved in age-related macular degeneration?
High HTRA1 expression is associated with cervical cell proliferation. Data indicate HtrA serine peptidase 1 (HTRA1) involvement in Age-related macular degeneration (AMD) pathogenesis. Variants in HTRA1 are not associated with age-related macular degeneration.What are the novel targets of HTRA1?
In addition, two novel targets of HTRA1 have been identified: EFEMP1, an extracellular matrix protein mutated in Doyne honeycomb retinal dystrophy, a genetic eye disease similar to AMD, and thrombospondin 1 (TSP1), an inhibitor of angiogenesis.What does HTRA3 stand for?
"Identification and cloning of two isoforms of human high-temperature requirement factor A3 (HtrA3), characterization of its genomic structure and comparison of its tissue distribution with HtrA1 and HtrA2". Biochem. J. 371 (Pt 1): 39–48. doi: 10.1042/BJ20021569.