Keyword Analysis & Research: icmetolazone

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Frequently Asked Questions

What is metolazone?

Metolazone is in a class of medications called diuretics ('water pills'). It causes the kidneys to reduce the amount of water and salt in the body by increasing the amount of urine. How should this medicine be used? Metolazone comes as a tablet to take by mouth.

How is metolazone administered in the treatment of edema?

Administration Metolazone is an oral agent, available in 2.5 mg, 5 mg, and 10 mg tablets. A dose of 5-20 mg once daily is recommended as the initial to treat edema associated with congestive heart failure or kidney disease. The dose should be titrated to the patient's response, then continued at the lowest dose needed to maintain diuresis.

Can you take Metolazone and colestipol at the same time?

If you are taking either of these drugs, separate metolazone from cholestyramine by at least 4 hours and from colestipol by at least 2 hours. If your condition persists or worsens, contact your doctor or pharmacist.

How does metolazone work as a loop diuretic?

Metolazone and a loop diuretic will synergistically enhance diuresis over the use of either agent alone. Using this combination, diuretic effects will occur at two different segments of the nephron; namely, the loop diuretic will act at the loop of Henle, and metolazone will act at the distal convoluted tubule.

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