Keyword Analysis & Research: vps35 gene


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What diseases are associated with the VPS35 gene?

Diseases associated with VPS35 include Parkinson Disease 17 and Hereditary Late-Onset Parkinson Disease . Among its related pathways are Signaling by GPCR and Signaling by Wnt . Gene Ontology (GO) annotations related to this gene include binding and obsolete protein transporter activity .

What does Vps35 stand for?

VPS35 (VPS35 Retromer Complex Component) is a Protein Coding gene. Diseases associated with VPS35 include Parkinson Disease 17 and Hereditary Late-Onset Parkinson Disease . Among its related pathways are Signaling by GPCR and Signaling by Wnt .

What is the function of vps35-vps26 and Vps29?

The VPS35-VPS26-VPS29 trimer forms the cargo recognition complex of the retromer. Vacuolar protein sorting ortholog 35 (VPS35) is a protein involved in autophagy and is implicated in neurodegenerative diseases, such as Parkinson's disease (PD) and Alzheimer's disease (AD).

How is vps35-pd clinically indistinguishable from Parkinson disease?

Except for a younger age of onset, VPS35 -PD is clinically indistinguishable from Parkinson disease of unknown cause (so-called sporadic Parkinson disease).

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